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TUSC3 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1797Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1797Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The TUSC3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TUSC3 protein expression profile in cells. The kit can be used for measuring the relative amounts of TUSC3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TUSC3.
Synonyms
Tumor suppressor candidate 3; Magnesium uptake/transporter TUSC3; Protein N33; TUSC3; N33
Gene Name
TUSC3
UniProt
Q13454
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.
Molecular Weight
39676 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Tumor suppressor candidate 3
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.

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