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MNK1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1383Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1383Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The MNK1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MNK1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MNK1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MNK1.
Synonyms
Kinase Mnk1; Map kinase interacting kinase; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MKNK1; MNK1
Gene Name
MKNK1
UniProt
Q9BUB5
Reactivity
Human, Mouse
Tissue Specificity
Ubiquitous.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
Molecular Weight
51342 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
MAP kinase-interacting serine/threonine-protein kinase 1
Subcellular Location
Isoform 2: Cytoplasm.

UniProtKB · Q9BUB5

MAP kinase-interacting serine/threonine-protein kinase 1

MKNK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BUB5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MKNK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
D3DQ20, D3DQ21, O00312, Q5TC06, Q5TC07, Q6V0N6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

CytoplasmNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Biological process

Translation regulation

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