MAGE-1 Colorimetric Cell-Based ELISA Kit

• Description:

  The MAGE-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MAGE-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MAGE-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MAGE-1.

• Synonyms:

  MAGE1; MAGE1A; MZ2-E; melanoma-associated antigen 1

• Gene Name:

  MAGEA1

• UniProt:

  P43355

• Reactivity:

  Human

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

• Molecular Weight:

  34342 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Melanoma-associated antigen 1

• Subcellular Location:

  Cytoplasm. Nucleus.