Interferon-gamma Receptor alpha Colorimetric Cell-Based ELISA Kit

• Description:

  The Interferon-gamma Receptor alpha Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Interferon-gamma Receptor alpha protein expression profile in cells. The kit can be used for measuring the relative amounts of Interferon-gamma Receptor alpha in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Interferon-gamma Receptor alpha.

• Synonyms:

  CD119 antigen; CDw119; IFN-gamma-R1; INGR; INGR1; Interferon-gamma receptor alpha chain precursor

• Gene Name:

  IFNGR1

• UniProt:

  P15260

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460) . Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114) . Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550) .

• Molecular Weight:

  54405 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Interferon gamma receptor 1

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein.