Mouse IFN Gamma / IFNG / Interferon gamma ELISA Kit PicoKine®

• Background:

  Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

• Description:

  Mouse IFN Gamma / IFNG / Interferon gamma ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse Ifng in cell culture supernatants and serum. Sensitivity: 5pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Interferon gamma; IFN-gamma; Ifng

• Gene Name:

  Interferon gamma

• UniProt:

  P01580

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: E.coli; Immunogen sequence: H23-C155

• Tissue Specificity:

  Released primarily from activated T lymphocytes.

• Applications:

  ELISA

• Field of Research:

  Cancer, Cytokines, Immunology, Innate Immunity, Interferons, Signaling Pathways, Stem Cells, TGF Beta, Tumor Immunology

• Sample Type:

  Cell culture supernatants and serum.

• Detection Range:

  31.2 pg/ml - 2,000 pg/ml

• Sensitivity:

  <5 pg/ml

• Function:

  Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  IFNG

• Subcellular Location:

  Secreted.

• Protein Name:

  Interferon gamma