Histone H2B Colorimetric Cell-Based ELISA Kit

• Description:

  The Histone H2B Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Histone H2B protein expression profile in cells. The kit can be used for measuring the relative amounts of Histone H2B in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Histone H2B.

• Synonyms:

  Histone H2B type F-S; Histone H2B.s; H2B/s; H2BFS

• Gene Name:

  HIST1H2BB

• UniProt:

  P33778

• Reactivity:

  Human, Mouse

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

• Molecular Weight:

  13950 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Histone H2B type 1-B

• Subcellular Location:

  Nucleus. Chromosome.