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HDAC10 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1261Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1261Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The HDAC10 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor HDAC10 protein expression profile in cells. The kit can be used for measuring the relative amounts of HDAC10 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on HDAC10.
Synonyms
Histone deacetylase 10; HD10
Gene Name
HDAC10
UniProt
Q969S8
Reactivity
Human, Mouse, Rat
Tissue Specificity
Ubiquitous. High expression in liver, spleen, pancreas and kidney.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Molecular Weight
71445 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Histone deacetylase 10
Subcellular Location
Cytoplasm. Nucleus. Excluded from the nucleoli.

UniProtKB · Q969S8

Polyamine deacetylase HDAC10

HDA10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q969S8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HDAC10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.5.1.48, 3.5.1.62
Processing
—
Secondary accessions
Q08AP4, Q6STF9, Q96P77, Q96P78, Q9H028, Q9UGX1, Q9UGX2
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

AutophagyDNA damageDNA recombinationDNA repair

Cellular component

CytoplasmNucleus

Molecular function

Hydrolase

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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