CAMK2A/CAMK2D Colorimetric Cell-Based ELISA Kit

• Description:

  The CAMK2A/CAMK2D Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CAMK2A/CAMK2D protein expression profile in cells. The kit can be used for measuring the relative amounts of CAMK2A/CAMK2D in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CAMK2A/CAMK2D.

• Synonyms:

  CAMK2A; CaM-kinase II alpha chain; CaMK-II alpha subunit; CaMKII-alpha; Calcium/calmodulin-dependent protein kinase type II alpha chain; KCC2A; kinase CaMK2-alpha

• Gene Name:

  CAMK2A

• UniProt:

  Q9UQM7

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) . Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378) . Activates FOXO3 transcriptional activity (By similarity) .

• Molecular Weight:

  54088 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Calcium/calmodulin-dependent protein kinase type II subunit alpha

• Subcellular Location:

  Cell junction, synapse, presynaptic cell membrane.Cell junction, synapse. Postsynaptic lipid rafts.