Anti-Clathrin, Light Chain CLTA Monoclonal Antibody

• Background:

  Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A B) . Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

• Description:

  Boster Bio Anti-Clathrin, Light Chain CLTA Monoclonal Antibody (Catalog # M05796) . Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human.

• Synonyms:

  Clathrin light chain A; Lca; CLTA

• Gene Name:

  CLTA and CLTB

• UniProt:

  P09496; P09497

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Purified recombinant N-terminal fragment of human Clathrin Light Chain

• Clonality:

  Monoclonal

• Clone:

  Clone: Clone: SPM174

• Applications:

  Flow Cytometry, IF, WB, IHC

• Field of Research:

  Coat Proteins, Neuroscience, Neurotransmission, Organelles, Protein Trafficking, Secretory Vesicles, Signal Transduction, Subcellular Markers, Tags & Cell Markers, Vesicle Transport

• Purification:

  200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

• Concentration:

  Purified antibody with BSA and azide at 200ug/ml

• Form:

  Liquid

• Function:

  Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.

• Molecular Weight:

  27077 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Fragment:

  IgG2b, kappa

• Other Gene Names:

  Clathrin light chain A

• Subcellular Location:

  Cytoplasmic