Anti-Coronin 1a Antibody

• Description:

  Boster Bio Anti-Coronin 1a Antibody catalog # M04245. Tested in IF, ICC, WB applications. This antibody reacts with Bovine, Human, Mouse, Pig, Rat.

• Synonyms:

  Coronin-1A; Coronin-like protein A; Clipin-A; Coronin-like protein p57; Tryptophan aspartate-containing coat protein; TACO; CORO1A; CORO1

• Gene Name:

  CORO1A

• UniProt:

  P31146

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse, Bovine, Pig

• Immunogen:

  C-terminal peptide of human coronin 1a couple to KLH

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed in brain, thymus, spleen, bone marrow and lymph node. Low in lung and gut.

• Applications:

  WB, IF, ICC

• Field of Research:

  Actin Assembly, Actin Binding Proteins, Actin, etc., Cell Type Markers, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction, Tags & Cell Markers

• Sensitivity:

  <10pg/ml

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Dilution:

  WB: 1:5,000, IF/ICC: 1:500-1:1,000

• Function:

  May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. .

• Molecular Weight:

  51026 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Coronin-1A

• Subcellular Location:

  Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cytoplasmic vesicle, phagosome membrane . In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity) . .