Anti-ASPP2 Rabbit Monoclonal Antibody

Anti-ASPP2 Rabbit Monoclonal Antibody

• Description: Boster Bio Anti-ASPP2 Rabbit Monoclonal Antibody catalog # M02609. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.
• Synonyms: Apoptosis-stimulating of p53 protein 2;Bcl2-binding protein;Bbp;Renal carcinoma antigen NY-REN-51;Tumor suppressor p53-binding protein 2;53BP2;p53-binding protein 2;p53BP2;TP53BP2;ASPP2, BBP;
• CAS Number: 9007-83-4
• Gene Name: Apoptosis-stimulating of p53 protein 2
• UniProt: Q13625
• Host: Rabbit
• Reactivity: Human
• Immunogen: A synthesized peptide derived from human ASPP2
• Clonality: Monoclonal
• Clone: Clone: AOEA-20
• Applications: WB,IHC,ICC,IF
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. .
• Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 125616 MW
• Observed Molecular Weight: 45 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200