Anti-Alpha-Synuclein SNCA Antibody

• Description:

  Boster Bio Anti-Alpha-Synuclein SNCA Antibody catalog # M00215-3. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Cow, Human, Mouse, Pig, Rat, Horse.

• Synonyms:

  Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; SNCA; NACP, PARK1

• Gene Name:

  SNCA

• UniProt:

  P37840

• Host:

  Chicken

• Reactivity:

  Cow, Human, Mouse, Pig, Rat, Horse

• Immunogen:

  Full length recombinant human protein expressed in and purified from E. coli

• Clonality:

  Polyclonal

• Tissue Specificity:

  Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

• Applications:

  IF, IHC, ICC, WB

• Field of Research:

  Alzheimer's Disease, Neurodegenerative Disease, Neurology Process, Neuroscience

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Dilution:

  WB: 1:2,000 IF/ICC and IHC: 1:1,000

• Function:

  May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

• Molecular Weight:

  14460 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Alpha-synuclein

• Subcellular Location:

  Cytoplasm, cytosol . Membrane . Nucleus . Cell junction, synapse . Secreted . Membrane-bound in dopaminergic neurons. .