Anti-Tau MAPT Rabbit Monoclonal Antibody

Anti-Tau MAPT Rabbit Monoclonal Antibody

• Description: Boster Bio Anti-Tau MAPT Rabbit Monoclonal Antibody catalog # M00097-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
• Synonyms: Microtubule-associated protein tau;Neurofibrillary tangle protein;Paired helical filament-tau;PHF-tau;MAPT;MAPTL, MTBT1, TAU;
• CAS Number: 9007-83-4
• Gene Name: Microtubule-associated protein tau
• UniProt: P10636
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthesized peptide derived from human Tau
• Clonality: Monoclonal
• Clone: Clone: GF-13
• Applications: WB,IHC,IP
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. .
• Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 78928 MW
• Observed Molecular Weight: 52 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:500-1:2000
  IHC 1:100-1:500
  IP 1:50