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Anti-SPIC Antibody

CAT: 0519-A13433Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A13433Size:100 µL
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Background
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression By similarity.

Carlsson R., Gene 299:271-278(2002).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Description
Boster Bio Anti-SPIC Antibody (Catalog # A13433) . Tested in WB applications. This antibody reacts with Human.
Synonyms
Transcription factor Spi-C; SPIC
Gene Name
SPIC
UniProt
Q8N5J4
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from internal of human SPIC.
Clonality
Polyclonal
Tissue Specificity
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver. .
Applications
WB
Field of Research
Domain Families, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Western blotting: 1:500~1:3000
Form
Liquid
Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity) . .
Molecular Weight
29180 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Transcription factor Spi-C
Subcellular Location
Nucleus .

UniProtKB · Q8N5J4

Transcription factor Spi-C

SPIC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N5J4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPIC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Molecular function

DNA-binding

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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