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Anti-CHML/Rep 2 Antibody

CAT: 0519-A08815Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A08815Size:100 µL
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Background
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Cremers F.P.M., Hum. Mol. Genet. 1:71-75(1992).
Kasper G., Gene 295:27-32(2002).
Ota T. Nat. Genet. 36:40-45(2004)
Description
Boster Bio Anti-CHML/Rep 2 Antibody (Catalog # A08815) . Tested in WB, IHC applications. This antibody reacts with Human.
Synonyms
Rab proteins geranylgeranyltransferase component A 2; Choroideremia-like protein; Rab escort protein 2; REP-2; CHML; REP2
Gene Name
CHML
UniProt
P26374
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from internal of human CHML.
Clonality
Polyclonal
Applications
WB, IHC
Field of Research
Neuroscience, Neurotransmission, Protein Trafficking, Secretory Vesicles, Signal Transduction, Vesicle Transport
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. .
Molecular Weight
74071 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Rab proteins geranylgeranyltransferase component A 2
Subcellular Location
Cytoplasm, cytosol .

UniProtKB · P26374

Rab proteins geranylgeranyltransferase component A 2

RAE2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26374
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHML
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RAB9, Q17RE0, Q9H1Y4
Protein keywords

Cellular component

Cytoplasm

Molecular function

GTPase activation

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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