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Anti-CIB2 Antibody

CAT: 0519-A08179-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A08179-1Size:100 µL
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Description
Boster Bio Anti-CIB2 Antibody (Catalog# A08179-1) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
CIB2; KIP2; Calcium and integrin-binding family member 2; Kinase-interacting protein 2; KIP 2
Gene Name
CIB2
UniProt
O75838
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A peptide derived from human CIB2. Immunogen sequence location: 21-70
Clonality
Polyclonal
Tissue Specificity
Widely expressed (PubMed:23023331) .
Applications
IHC-P, IF (paraffin), ELISA
Field of Research
Calcium Binding Proteins, Calcium Signaling, Signal Transduction, Signaling Pathway
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Function
Calcium-binding protein critical for proper photoreceptor cell maintenance and function. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970) . May be involved in the mechanotransduction process (By similarity) .
Molecular Weight
21644 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
Calcium and integrin-binding family member 2
Subcellular Location
Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma. Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ) (By similarity) . Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells (PubMed:26173970) .

UniProtKB · O75838

Calcium and integrin-binding family member 2

CIB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75838
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CIB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DDF0, H0YM71, Q05BT6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMagnesiumMetal-binding

Cellular component

Cell membraneCell projectionCiliumCytoplasmMembrane

Disease

DeafnessDisease variantNon-syndromic deafnessRetinitis pigmentosaUsher syndrome

Domain

Repeat

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