Anti-Protein SMG7 SMG7 Antibody

• Background:

  Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.
  
  Ohnishi T., Mol. Cell 12:1187-1200(2003).
  Nagase T., DNA Res. 3:321-329(1996).
  Nakajima D., DNA Res. 9:99-106(2002).

• Description:

  Boster Bio Anti-Protein SMG7 SMG7 Antibody (Catalog # A06078) . Tested in WB, IF applications. This antibody reacts with Human.

• Synonyms:

  Protein SMG7; EST1-like protein C; SMG-7 homolog; hSMG-7; SMG7; C1orf16, EST1C, KIAA0250

• Gene Name:

  SMG7

• UniProt:

  Q92540

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthesized peptide derived from internal of human SMG7.

• Clonality:

  Polyclonal

• Applications:

  WB, IF

• Field of Research:

  Epigenetics and Nuclear Signaling, RNA Processing

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. .

• Molecular Weight:

  127282 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Protein SMG7

• Subcellular Location:

  Cytoplasm. Nucleus. Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm.