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Anti-RAP2A Antibody

CAT: 0519-A03547Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0519-A03547Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-RAP2A Antibody (Catalog# A03547) . Tested in WB application (s) . This antibody reacts with Human.
Synonyms
Ras-related protein Rap-2a; RbBP-30; RAP2A
Gene Name
RAP2A
UniProt
P10114
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant RAP2A protein
Clonality
Polyclonal
Applications
WB
Field of Research
G Protein Signaling, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins
Purification
Protein A Chromatography
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution
Western blot: 1-2 µg/ml
Form
Liquid
Function
Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. .
Molecular Weight
20615 MW
Shipping Conditions
Available
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
Ras-related protein Rap-2a
Subcellular Location
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995) . Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443) .
Protein Name
Ras-related protein Rap-2a

UniProtKB · P10114

Ras-related protein Rap-2a

RAP2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P10114
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RAP2A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.5.2
Processing
Precursor
Secondary accessions
B2RCJ1, Q5JSC1, Q5JSC2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneCell projectionEndosomeGolgi apparatusLysosomeMembrane

PTM

GlycoproteinLipoproteinMethylationPalmitatePrenylationUbl conjugation

Ligand

GTP-bindingNucleotide-binding

Molecular function

Hydrolase

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