Anti-ASK1 (Ab-966) MAP3K5 Antibody

• Background:

  Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
  
  Zhang W, et al. (2005) J Biol Chem. 280(19): 19036-19044.
  Fujii K, et al. (2004) Oncogene. 23(29):5099-5104.
  Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12; 279(11): 10442-10449.
  Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96(15): 8511-8515.

• Description:

  Boster Bio Anti-ASK1 (Ab-966) MAP3K5 Antibody (Catalog # A00929-2) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

• Gene Name:

  MAP3K5

• UniProt:

  Q99683

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Peptide sequence around aa.964~968 (S-I-S-L-P) derived from Human ASK1.

• Clonality:

  Polyclonal

• Applications:

  WB, IHC, IF

• Field of Research:

  Apoptosis, Cardiovascular, Cell Biology, Hypertrophy, Intracellular, Kinases

• Purification:

  Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.