Anti-CD152 CTLA4 Antibody

• Description:

  Boster Bio Anti-CD152 CTLA4 Antibody catalog # A00020. Tested in IHC applications. This antibody reacts with Human.

• Synonyms:

  Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4; CD152

• Gene Name:

  CTLA4

• UniProt:

  P16410

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide from human protein at AA range: 41-90

• Tissue Specificity:

  Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. .

• Applications:

  IHC

• Purification:

  Immunogen affinity purified

• Dilution:

  IHC-P, 1:50-300

• Form:

  Liquid

• Function:

  Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. .

• Molecular Weight:

  24656 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Cytotoxic T-lymphocyte protein 4

• Subcellular Location:

  Cell membrane ; Single-pass type I membrane protein . Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalisation; .