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CD152 Antibody / CTLA4

CAT: 0800-RQ5483Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ5483Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The CTLA4 gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P16410
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide specific to human CD152 / CTLA4 was used as the immunogen for the CD152 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ADCD-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CD152 antibody at -20oC.
Limitations
This CD152 antibody is available for research use only.
Storage Conditions
Store the CD152 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CD152 antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse NIH3T3 cell lysate with CD152 antibody. Predicted molecular weight ~25 kDa but may be observed at higher molecular weights due to glycosylation.

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