Mouse Plexin B2/PLXNB2 ELISA Kit PicoKine®

• Background:

  Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene. It is mapped to 15 E3; 15 44.68 cM. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins.

• Description:

  Mouse Plexin B2 ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse Plxnb2 in cell culture supernatants, serum and plasma (heparin, EDTA) . Sensitivity: 0.1ng/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Plexin-B2; Plxnb2

• Gene Name:

  Plexin B2

• UniProt:

  B2RXS4

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: CHO; Immunogen sequence: L20-P1201

• Tissue Specificity:

  Detected in macrophages from spleen and bone marrow (at protein level) . Detected in granule cells in the developing cerebellum, dentate gyrus and olfactory bulb.

• Applications:

  ELISA

• Field of Research:

  Axonal Guidance Proteins, Cell Type Marker, Growth and Development, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience

• Sample Type:

  Cell culture supernatants, serum and plasma (heparin, EDTA) .

• Detection Range:

  0.78 ng/ml - 50 ng/ml

• Sensitivity:

  <50 pg/ml

• Function:

  Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  Plxnb2

• Subcellular Location:

  Cell membrane, Single-pass type I membrane protein