Mouse Plexin C1/PLXNC1 ELISA Kit PicoKine®

• Background:

  A Plexin is a protein which acts as a receptor for Semaphorin family signaling proteins. This gene is mapped to 10; 10 C2. It is classically known for its expression on the surface of axon growth cones and involvement in signal transduction to steer axon growth away from the source of Semaphorin. Plexin also has implications in development of other body systems by activating GTPase enzymes to induce a number of intracellular biochemical changes leading to a variety of downstream effects.

• Description:

  Mouse Plexin C1 ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse Plxnc1 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate) . Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Plexin-C1; Virus-encoded semaphorin protein receptor; CD232; Plxnc1; Vespr

• Gene Name:

  Plexin C1

• UniProt:

  Q9QZC2

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: A35-T950

• Tissue Specificity:

  Detected on dendritic cells, skin Langerhans cells and neutrophils.

• Applications:

  ELISA

• Field of Research:

  Cancer, Cell Adhesion, Invasion/Microenvironment

• Sample Type:

  Cell culture supernatants, serum and plasma (heparin, EDTA, citrate) .

• Detection Range:

  93.8 pg/ml - 6,000 pg/ml

• Sensitivity:

  <50 pg/ml

• Function:

  Receptor for SEMA7A, for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  Plxnc1

• Subcellular Location:

  Membrane, Single-pass type I membrane protein