Mouse Plexin C1/PLXNC1 ELISA Kit PicoKine®, Carrier-free

• Background:

  A Plexin is a protein which acts as a receptor for Semaphorin family signaling proteins. This gene is mapped to 10; 10 C2. It is classically known for its expression on the surface of axon growth cones and involvement in signal transduction to steer axon growth away from the source of Semaphorin. Plexin also has implications in development of other body systems by activating GTPase enzymes to induce a number of intracellular biochemical changes leading to a variety of downstream effects.

• :

  heparin or EDTA

• Description:

  Mouse Plexin C1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Plxnc1 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate ). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	168	149	160	163	160	6.96	4.3%
  Sample 2	824	814	878	902	854	36.67	4.2%
  Sample 3	2614	2932	2991	2861	2849	143.54	5.0%

  *number of samples for each test n=16.

• Synonyms:

  Plexin-C1; Virus-encoded semaphorin protein receptor; CD232; Plxnc1; Vespr

• Gene Name:

  plexin C1

• Gene ID:

  54712

• UniProt:

  Q9QZC2

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: A35-T950

• Tissue Specificity:

  Detected on dendritic cells, skin Langerhans cells and neutrophils.

• Applications:

  ELISA

• Standard:

  10 ng/tube

• Sample Type:

  cell culture supernatants, serum and plasma (heparin, EDTA, citrate ).

• Detection Range:

  93.8 pg/ml - 6,000 pg/ml

• Sensitivity:

  <50 pg/ml

• Function:

  Receptor for SEMA7A, for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.

• Components:

  Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

• Storage Conditions:

  Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Specificity:

  Natural and recombinant mouse Plexin C1

• Subcellular Location:

  Membrane, Single-pass type I membrane protein