Human Vitamin D BP/GC/Vitamin D Binding Protein ELISA Kit PicoKine®

• Background:

  Vitamin D-binding protein, also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene.The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues.

• Description:

  Human Vitamin DBP ELISA Kit PicoKine® (96 Tests) . Quantitate Human GC in cell culture supernatants, serum, plasma (heparin, EDTA), saliva, urine and human milk. Sensitivity: 150pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Vitamin D-binding protein; DBP; VDB; Gc protein-derived macrophage activating factor

• Gene Name:

  GC, vitamin D binding protein

• UniProt:

  P02774

• Reactivity:

  Human

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: L17-L474

• Tissue Specificity:

  Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine.

• Applications:

  ELISA

• Sample Type:

  Cell culture supernatants, serum, plasma (heparin, EDTA), saliva, urine and human milk.

• Detection Range:

  1.56 ng/ml - 100 ng/ml

• Sensitivity:

  <150 pg/ml

• Function:

  Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  GC

• Subcellular Location:

  Secreted.