EB1002

CAT: 0804-HY-P10746-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-P10746-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

EB1002 is a selective NK2R agonist. EB1002 significantly raises the expression levels of mitochondrial biosynthesis-related genes (like PGC-1α) in obese mice, indicating that it promotes energy expenditure by boosting mitochondrial activity. EB1002 also increases the insulin sensitivity and improves glycolipid metabolism of the mice. EB1002 is promising for research of obesity and type 2 diabetes[1].

CAS Number

2770688-48-5

UNSPSC

12352209

Target

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/eb1002.html

Purity

99.98

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 48.78 mg/mL (adjust pH to 3 with 1 M HCl)

Smiles

O=C(CCCCCCCCCCCCCCCCC(O)=O)N[C@H](C(O)=O)CCC(NCCOCCOCC(NCCOCCOCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C(C)C)C(NCC(N(C)[C@@H](CC(C)C)C(N[C@@H](CCOC)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C73H124N12O23

Molecular Weight

1537.83

References & Citations

[1]Sass F, et al. NK2R control of energy expenditure and feeding to treat metabolic diseases. Nature. 2024 Nov;635 (8040) :987-1000.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

NK2R

Related Products

Catalog	Name
HY-P991641	IMC-EB10

Alternative Products

Catalog	Name
T201621-01	EB1002

EB1002

Related Products

Alternative Products

Popular Products