Products for Research Use Only

EB1002

CAT: 0931-T201621-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201621-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2770688-48-5
Target
E3 Ligase Ligand-Linker Conjugate, Neurokinin receptor
Related Pathways
Neuroscience, GPCR/G Protein, PROTAC
Bioactivity
EB1002 is a selective NK2R agonist that has demonstrated significant enhancements in the expression levels of genes associated with mitochondrial biogenesis (such as PGC-1α) in obese mice. This suggests that EB1002 promotes energy expenditure by enhancing mitochondrial activity. Additionally, EB1002 has improved insulin sensitivity and glucose-lipid metabolism in mice. Therefore, EB1002 holds potential for research into obesity and type 2 diabetes.
Smiles
[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)=O)=O)CC(O)=O)=O)CCCCN)=O)C(N[C@H](C(NCC(N([C@H](C(N[C@@H](CCOC)C(N)=O)=O)CC(C)C)C)=O)=O)[C@@H](C)C)=O
Molecular Formula
C73H124N12O23
Molecular Weight
1537.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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