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Zeaxanthin dipalmitate

CAT: 0804-HY-N9182-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N9182-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (Kd=81.2 nM) and adiponectin receptor 1 (AdipoR1; Kd=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) [1][2].
CAS Number
144-67-2
Product Name Alternative
Physalien
UNSPSC
12352211
Target
Adiponectin Receptor; Autophagy; P2X Receptor
Type
Natural Products
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zeaxanthin-dipalmitate.html
Purity
99.9
Smiles
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](OC(CCCCCCCCCCCCCCC)=O)CC2(C)C)=C(C)C[C@@H](OC(CCCCCCCCCCCCCCC)=O)C1
Molecular Formula
C72H116O4
Molecular Weight
1045.69
References & Citations
[1]Gao H, et al. Wolfberry-Derived Zeaxanthin Dipalmitate Attenuates Ethanol-Induced Hepatic Damage. Mol Nutr Food Res. 2019 Jun;63 (11) :e1801339.|[2]Liu F, et al. Wolfberry-derived zeaxanthin dipalmitate delays retinal degeneration in a mouse model of retinitis pigmentosa through modulating STAT3, CCL2 and MAPK pathways. J Neurochem. 2021 Sep;158 (5) :1131-1150.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
P2X7 Receptor

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