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ITGB2/LFA-1 Antibody

CAT: 0013-GTR18125255Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18125255Size:0.1 mg
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Description
ITGB2/LFA-1 Antibody
Product Name Alternative
ITGB2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor), cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, complement receptor C3 beta-subunit, complement receptor C3 subunit beta, integrin beta chain, beta 2, integrin beta-2, leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
UniProt
P05107
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-ETQEDHNGGQKQLS
Target
ITGB2 / LFA-1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Molecular Weight
Approx 90kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 90kDa band observed in lysates of cell lines K562 and U937 (calculated MW of 84.8kDa according to NP_00202.2) . Recommended concentration: 0.3-1μg/mL.
Tested Applications
ELISA, WB
NCBI Accession Number
NP_000202.2
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · P05107

Integrin beta-2

ITB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05107
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B3KTS8, D3DSM1, Q16418, Q53HS5, Q9UD72
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

CalciumMagnesiumMetal-binding

Biological process

Cell adhesionPhagocytosis

Cellular component

Cell membraneMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoproteinPyrrolidone carboxylic acid

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

IntegrinReceptor

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