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Lenalidomide nonanedioic acid

CAT: 0804-HY-161451Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161451Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lenalidomide nonanedioic acid is a conjugate of the E3 ligase ligand and linker of LHF418. Lenalidomide nonanedioic acid can be used as a key intermediate for the synthesis of intact PROTACs molecules[1].
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenalidomide-nonanedioic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCCCCC(NC1=C2C(C(N(C3CCC(NC3=O)=O)C2)=O)=CC=C1)=O
Molecular Formula
C22H27N3O6
Molecular Weight
429.47
References & Citations
[1]Li H, et al. Discovery of LHF418 as a new potent SOS1 PROTAC degrader. Bioorg Med Chem. 2024 Apr 1;103:117661. doi: 10.1016/j.bmc.2024.117661. Epub 2024 Mar 2. PMID: 38489998.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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