FOXO1-IN-3
CAT:
804-HY-153617-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FOXO1-IN-3
- CAS Number: 2451093-95-9
- UNSPSC Description: FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1].
- Target Antigen: FOXO
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/foxo1-in-3.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=C(N2CCN(CC2)C)C=C1)NC3=CC(C4=NC5=C(N4)C=CC=C5)=NN3
- Molecular Weight: 401.46
- References & Citations: [1]Lee YK, et al. FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice. Mol Metab. 2021 Jul;49:101187.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported