Thalidomide-4-O-C2-NH2 (hydrochloride)

Thalidomide-4-O-C2-NH2 (hydrochloride)

• CAS Number: 2341840-99-9
• UNSPSC Description: Thalidomide-4-O-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-4-o-c2-nh2-hydrochloride.html
• Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCN)=O.[H]Cl
• Molecular Weight: 353.762
• References & Citations: [1]Turk BE, et al. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production. Proc Natl Acad Sci U S A. 1996;93(15):7552‐7556.
• Shipping Conditions: Room Temperature