CORM-A1

• Description:

  CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the investigation of CO's impact on cellular systems. As CO is generated from heme degradation by the enzyme heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only exhibits anti-oxidant and anti-inflammatory properties but also regulates CO release in a manner dependent on pH and temperature, promoting mild vasorelaxation and hypotension. Furthermore, CORM-A1 has been shown to provide cytoprotection in primary cultures of astrocytes under oxidative stress while also enhancing autophagy due to its boron-containing composition.

• Product Name Alternative:

  Sodium boranocarbonate

• UNSPSC:

  12352300

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/corm-a1.html

• Purity:

  95.0

• Solubility:

  H2O : 50 mg/mL

• Smiles:

  [Na][Na].O=C=O.B

• Molecular Formula:

  Na2 (H3BCO2)

• Molecular Weight:

  103.82

• Precautions:

  H302, H315, H319, H335

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [17363-08-5]