CORM-A1

CAT: 0804-HY-W782399Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W782399Size:10 mg
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Description
CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the investigation of CO's impact on cellular systems. As CO is generated from heme degradation by the enzyme heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only exhibits anti-oxidant and anti-inflammatory properties but also regulates CO release in a manner dependent on pH and temperature, promoting mild vasorelaxation and hypotension. Furthermore, CORM-A1 has been shown to provide cytoprotection in primary cultures of astrocytes under oxidative stress while also enhancing autophagy due to its boron-containing composition.
CAS Number
[17363-08-5]
Product Name Alternative
Sodium boranocarbonate
UNSPSC
12352300
Hazard Statement
H302, H315, H319, H335
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/corm-a1.html
Purity
95.0
Solubility
H2O : 50 mg/mL
Smiles
[Na][Na].O=C=O.B
Molecular Formula
Na2 (H3BCO2)
Molecular Weight
103.82
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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