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P18SMI-21

CAT: 0804-HY-116923Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116923Size:1 Each
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Description
P18SMI-21 is a novel INK4C inhibitor that specifically blocks the biological activity of p18 protein. p18SMI-21 exerts its anti-gastric acid effect through direct contact, and the intensity of this effect varies with the dose. p18SMI-21 can significantly reduce the proteolytic activity of pepsin under certain conditions. The inhibitory effect of p18SMI-21 is best achieved in direct contact with the substrate. If it contacts the substrate first, the inhibitory effect will be lost[1].
CAS Number
20535-76-6
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/p18smi-21.html
Smiles
CC(NC1=CC=C(C=C1)S(=O)(NCCO)=O)=O
Molecular Formula
C10H14N2O4S
Molecular Weight
258.29
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1][Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--) -alpha-bisabolol (author's transl) ]
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

N-(4-{[(2-hydroxyethyl)amino]sulfonyl}phenyl)acetamide
CAS Number20535-76-6
PubChem CID2794794
IUPAC NameN-[4-(2-hydroxyethylsulfamoyl)phenyl]acetamide
Molecular FormulaC10H14N2O4S
Molecular Weight258.30
XLogP-0.4
Topological Polar Surface Area104
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count17
Formal Charge0
Complexity342
SMILES
CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NCCO
InChI
InChI=1S/C10H14N2O4S/c1-8(14)12-9-2-4-10(5-3-9)17(15,16)11-6-7-13/h2-5,11,13H,6-7H2,1H3,(H,12,14)
InChIKey
VUYBWFBHHFQGDM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(4-{[(2-hydroxyethyl)amino]sulfonyl}phenyl)acetamide
CAS: 20535-76-6
CID: 2794794
Formula: C10H14N2O4S
MW: 258.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight258.30
XLogP3-0.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass258.06742811
Monoisotopic Mass258.06742811
Topological Polar Surface Area104 Ų
Heavy Atom Count17
Formal Charge0
Complexity342
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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