Maslinic acid

• Description :

  Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.

• CAS Number :

  [4373-41-5]

• Product Name Alternative :

  Crategolic acid; 2α-Hydroxyoleanolic acid

• UNSPSC :

  12352211

• Target :

  Bacterial; Endogenous Metabolite; HIV; NF-κB

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Inflammation/Immunology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Maslinic-acid.html

• Purity :

  99.87

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C[C@]([C@@]1([H])[C@]2(C[C@@H](O)[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@@](C4=CC1)(CC[C@]5(C(O)=O)[C@@]4([H])CC(C)(C)CC5)C

• Molecular Formula :

  C30H48O4

• Molecular Weight :

  472.70

• References & Citations :

  [1]Fukumitsu S, et al. Anti-inflammatory and anti-arthritic effects of pentacyclic triterpenoids maslinic acid through NF-κB inactivation. Mol Nutr Food Res. 2016 Feb;60 (2) :399-409.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  RelA/p65