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244cis

CAT: 0804-HY-160552Size: 1 mg (25.76 mM x 40 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-160552Size:1 mg (25.76 mM x 40 μL in Ethanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs) . LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels[1].
CAS Number
2956402-64-3
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/244cis.html
Concentration
25.76 mM * 40 μL in Ethanol
Purity
96.70
Solubility
10 mM in DMSO
Smiles
CCCCCC/C=C\COC(CCCCCCCCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCN1CCN(CC1)CCCCCCCCC(OC/C=C\CCCCCC)=O)=O
Molecular Formula
C60H111N3O6
Molecular Weight
970.54
References & Citations
[1]Kim M, et al. Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety. Bioeng Transl Med. 2023 May 28;8 (6) :e10556.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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CatalogName
T84669-01244cis

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