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NIR-Red Dead Cell-1 Dye

CAT: 0804-HY-D0917-01Size: 161 μg (5 mM x 50 μL in DMSO)Dry Ice: NoHazardous: No
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CAT#:0804-HY-D0917-01Size:161 μg (5 mM x 50 μL in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NIR-Red Dead Cell-1 Dye is a DNA-binding fluorescent dye for non-living cells (Ex/Em=515 nm/531 nm) . NIR-Red Dead Cell-1 Dye can intercalate into base pairs of double-stranded DNA and produce stronger fluorescence. NIR-Red Dead Cell-1 Dye is suitable for necrotic cells or late apoptotic cells with damaged cell membranes, showing green fluorescence under fluorescence microscopy or flow cytometry. NIR-Red Dead Cell-1 Dye can be used to distinguish live cells from dead cells and distinguish cell membrane integrity. NIR-Red Dead Cell-1 Dye can be attached to the surface of Feraheme (FH) nanoparticles (NPs) to obtain fluorescent dye-functionalized NPs for drug delivery studies[1][2][3].
CAS Number
157199-59-2
UNSPSC
12171500
Target
DNA Stain
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/to-pro-1.html
Concentration
5 mM * 50 μL in DMSO
Purity
96.0
Solubility
10 mM in DMSO
Smiles
C[N+](CCC[N+]1=C2C=CC=CC2=C(/C=C3SC4=CC=CC=C4N\3C)C=C1)(C)C.[I-].[I-]
Molecular Formula
C24H29I2N3S
Molecular Weight
645.38
References & Citations
[1]Hoonsung Cho, et al. Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems. ACS Nano. 2013 Mar 26;7 (3) :2032-41.|[2]Gorokhova E, et al. A comparison of TO-PRO-1 iodide and 5-CFDA-AM staining methods for assessing viability of planktonic algae with epifluorescence microscopy. J Microbiol Methods. 2012 Jun;89 (3) :216-21.|[3]Okochi M, et al. Fluorometric observation of viable and dead adhering diatoms using TO-PRO-1 iodide and its application to the estimation of electrochemical treatment. Applied microbiology and biotechnology 51 (1999) : 364-369.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, protect from light, 2 years
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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