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S1H

CAT: 0804-HY-P10283-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10283-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S1H, a mimetic of hGH, is a human growth hormone receptor (hGHR) antagonist. S1H inhibits the interaction of hGH with hGHR. S1H inhibits phosphorylation of STAT5 in cells co-treated with hGH[1].
UNSPSC
12352209
Target
GHR; STAT
Type
Peptides
Related Pathways
JAK/STAT Signaling; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/s1h.html
Purity
99.29
Solubility
H2O : 17.4 mg/mL (ultrasonic; warming)
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CO)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N5[C@@H](CCC5)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C
Molecular Formula
C94H141N23O27
Molecular Weight
2025.26
References & Citations
[1]Basu R, et al. A novel peptide antagonist of the human growth hormone receptor. J Biol Chem. 2021 Jan-Jun;296:100588.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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