Products for Research Use Only
RegisterLogin

ST2-IN-1

CAT: 0804-HY-168532-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-168532-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ST2-IN-1 (compound 31) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 7 μM in AlphaLISA assay, and 7.19 μM in HEK-Blue assay. ST2-IN-1 effectively attenuats the ST2/IL-33 signaling in human mast cells[1].
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/st2-in-1.html
Concentration
10mM
Purity
99.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C1=CC=C(C=C1)C2CCCN2CC3=CC=C(N3)C4=CC=C(C(N5CCCC5)=C4)[N+]([O-])=O)C
Molecular Formula
C27H33N5O2
Molecular Weight
459.58
References & Citations
[1]Xinrui Yuan, et al. Studies of Structure–Activity Relationship of 2- (Pyrrolidin-1ylmethyl) -1H-pyrrole-Based ST2 Inhibitors and Their Inhibition of Mast Cells Activation. ACS Med. Chem. Lett. October 18, 2024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P76090ST2/IL1RL1, Human (HEK293)
HY-P87275-01ST2 Antibody (YA6958, Mouse)
HY-P76093ST2/IL1RL1, Human (HEK293, His)
HY-P72459-01ST2/IL1RL1, Mouse (HEK293, His)
HY-P76660-01ST2/IL1RL1, Cynomolgus (HEK293, His)
HY-P76661-01ST2/IL1RL1, Mouse (HEK293, Fc)
HY-P76091-01ST2/IL1RL1, Human (HEK293, Fc)
HY-P70615-01ST2/IL1RL1, Human (310a.a, HEK293, His)
HY-P76662ST2/IL1RL1, Mouse (306a.a, HEK293, His)
HY-P705138-01ST2/IL1RL1, Human (Biotinylated, HEK293, Fc-Avi)

Alternative Products

CatalogName
T200866-01ST2-IN-1
DT0051ST2
146934Il1rl1, Control Peptide (Interleukin-1 Receptor-like 1, Lymphocyte Antigen 84, Protein ST2, Protein T1, Ly84, St2, Ste2, DER4, Fit-1, ST2, ST2L, St2-rs1, T1, T1/ST2, T1 gene)
299251ST2 (IL-1 R4, T1)
10-2322ST2 antibody
MBS152624-01ST2 Peptide
GTR18245772-01Anti-ST2

Popular Products