ST2-IN-1

CAT: 0931-T200866-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T200866-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Interleukin

Related Pathways

Immunology/Inflammation

Bioactivity

ST2-IN-1 (compound 31) is an inhibitor of Stimulation-2 (ST2) with an IC50 of 7 μM in AlphaLISA assays and 7.19 μM in HEK-Blue assays. This compound effectively attenuates the ST2/IL-33 signaling pathway in human hypertrophic cells.

Smiles

N(CC1=CC=C(/C=C/C(O)=O)C=C1)(CC)C2=C(C=CC(C(F)(F)F)=C2)N3CC=4C(CC3)=CC(O)=CC4

Molecular Formula

C27H33N5O2

Molecular Weight

459.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-168532-01	ST2-IN-1
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