HIF-2α-IN-8
CAT:
804-HY-148860-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HIF-2α-IN-8
- CAS Number: 2734922-78-0
- UNSPSC Description: HIF-2α-IN-8 is a potent and orally active HIF2α inhibitor with IC50 values of 9, 37, 246 nM for HIF2α SPA, HIF2α iScript, HIF2α HRE RGA, respectively. HIF-2α-IN-8 shows antitumor activity[1].
- Target Antigen: HIF/HIF Prolyl-Hydroxylase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hif-2α-in-8.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: FC1(C2=C(Cl)N=CC=C2[C@]3(CC1)N=C4N(C=C(C=C4OC(F)F)C(F)(F)F)C3)F
- Molecular Weight: 441.73
- References & Citations: [1]Robin Alec Fairhurst, et al. Compounds and compositions for inhibiting the activity of hif2-alpha and their methods of use. WO2021220170A1.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported