Magainin 1

• Description :

  Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria[1][2][3].

• Product Name Alternative :

  Magainin I

• UNSPSC :

  12352209

• Target :

  Antibiotic; Bacterial; Fungal

• Type :

  Peptides

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/Magainin_1.html

• Purity :

  99.92

• Solubility :

  H2O : 50 mg/mL

• Smiles :

  [C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCCCN)=O)CCSC)=O)[C@H](CC)C)=O)CCC(O)=O)=O)=O)C(C)C)=O)=O)C)=O)CCCCN)=O)=O)=O)CCCCN)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)NC([C@@H](NC(CNC([C@@H](NC(CN)=O)[C@H](CC)C)=O)=O)CCCCN)=O

• Molecular Formula :

  C112H177N29O28S

• Molecular Weight :

  2409.85

• References & Citations :

  [1]Duclohier H, et al. Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers. Biophys J. 1989 Nov;56 (5) :1017-21.|[2]Matsuzaki K, et al. Magainin 1-induced leakage of entrapped calcein out of negatively-charged lipid vesicles. Biochim Biophys Acta. 1989 May 19;981 (1) :130-4.|[3]Zasloff M, et al. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A. 1987 Aug;84 (15) :5449-53.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [108433-99-4]