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Methyl pheophorbide a

CAT: 0804-HY-N10902-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N10902-01Size:1 mg
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Description
Methyl pheophorbide a is a natural product, one of the chlorophyll-a derivatives. Methyl pheophorbide a is a photosensitizer that produces singlet oxygen and reactive oxygen species (ROS) under light of specific wavelength, thereby leading to cell death[1][2][3].
CAS Number
5594-30-9
UNSPSC
12352005
Target
Apoptosis; Caspase; Photosensitizer; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/methyl-pheophorbide-a.html
Purity
99.57
Solubility
10 mM in DMSO
Smiles
COC([C@@H]1/C2=C([C@H]([C@@H]3C)CCC(OC)=O)/N=C3/C=C(C(C)=C/4C=C)\NC4=C/C5=N/C(C(CC)=C5C)=C\C6=C(C)C(C1=O)=C2N6)=O
Molecular Formula
C36H38N4O5
Molecular Weight
606.71
References & Citations
[1]F.C. Pennington, et al. Preparation and Properties of Pyrochlorophyll a, Methyl Pyrochlorophyllide a, Pyropheophytin a, and Methyl Pyropheophorbide a Derived from Chlorophyll by Decarbomethoxylation. J. Am. Chem. Soc. 1964, 86, 7, 1418-1426.|[2]ShinOgasawara, et al. C132-Methylation of methyl pheophorbide a and stereoselective preparation of methyl (132R) -methylpyropheophorbide a. Tetrahedron Letters, 2014, 3618-3621.|[3]Ha J Y, et al. Isolation, identification, and apoptosis activity of the photosensitizer methyl pheophorbide A from Perilla frutescens leaves[J]. Applied Biological Chemistry, 2022, 65 (1) : 52.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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