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Recombinant Human Eotaxin-2/CCL24

CAT: 0355-AP60317Size: InquireDry Ice: NoHazardous: No
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CAT#:0355-AP60317Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CCL24 is a secreted protein, encoded by CCL24 gene in humans located on Chr.7, and produced by activated monocytes and T lymphocytes. CCL24 has functions of chemotactic activity for resting T-lymphocytes and eosinophils, but none for monocytes and activated lymphocytes. The plasma levels of CCL24 and the aspirin-exacerbated respiratory disease (such as asthma) morbidity rate have positive correlation.
Product Name Alternative
CK-beta-6, MPIF-2, Small-inducible Cytokine A24
Gene ID
6369
UniProt
O00175
Target
VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
Purification
> 97 % by SDS-PAGE and HPLC analyses.
Endotoxin
Less than 1 EU/ugof rHuEotaxin-2/CCL24 as determined by LAL method.
Bioactivity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration of 50-100 ng/ml.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculated Molecular Weight
Approximately 8.8 kDa, a single non-glycosylated polypeptide chain containing 78 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Host or Source
Escherichia coli

UniProtKB · O00175

C-C motif chemokine 24

CCL24_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00175
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCL24
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R5K2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

ChemotaxisInflammatory response

Molecular function

Cytokine

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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