CL2-SN-38

CL2-SN-38

• CAS Number: 1036969-20-6
• UNSPSC Description: CL2-SN-38 is a cleavable linker-based agent-Linker conjugate, it can conjugate with the anti-Trop-2-humanized antibody hRS7. CL2-SN-38 can be used for the reasearch of cancer[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cl2-sn-38.html
• Purity: 99.36
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C1N(CC2=C3CC)C(C2=NC4=CC=C(O)C=C34)=CC([C@@](CC)5OC(OCC6=CC=C(NC([C@H](CCCCN)NC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C(CNC(C8CCC(CN(C9=O)C(C=C9)=O)CC8)=O)N=N7)=O)=O)CC%10=CC=CC=C%10)=O)=O)C=C6)=O)=C1COC5=O
• Molecular Weight: 1627.79
• References & Citations: [1]Cardillo TM, et al. Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. Clin Cancer Res. 2011 May 15;17(10):3157-69.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported