Carnosic acid

• Description:

  Carnosic acid is an orally active lipid absorption inhibitor. Carnosic acid has demonstrated inhibition of oxidative stress and inflammation, suppression of cell proliferation, and antibacterial activity.

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Apoptosis; Bacterial

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Carnosic_acid.html

• Purity:

  99.53

• Solubility:

  DMSO : 130 mg/mL (ultrasonic)

• Smiles:

  OC([C@@]([C@@]1([H])CCC2=CC(C(C)C)=C3O)(CCCC1(C)C)C2=C3O)=O

• Molecular Formula:

  C20H28O4

• Molecular Weight:

  332.43

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Yesil-Celiktas O, et al. Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines. Plant Foods Hum Nutr. 2010 Jun;65 (2) :158-63.|[2]Kiyofumi Ninomiya, et al. Carnosic acid, a new class of lipid absorption inhibitor from sage. Bioorg Med Chem Lett. 2004 Apr 19;14 (8) :1943-6.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C, stored under nitrogen

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [3650-09-7]