Boc-Arg-Val-Arg-Arg-AMC (hydrochloride)

• UNSPSC Description:

  Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin[1].

• Target Antigen:

  Furin

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/boc-arg-val-arg-arg-amc-hydrochloride.html

• Purity:

  99.18

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC(OC(C)(C)C)=O)=O)=O)=O)=O)C=C1O2)=CC2=O.Cl

• Molecular Weight:

  879.45

• References & Citations:

  [1]Wanyiri JW, et al. Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity. Infect Immun. 2007 Jan;75(1):184-92.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  136132-77-9