Boc-Gln-Arg-Arg-AMC

• CAS Number:

  109376-05-8

• UNSPSC Description:

  Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/boc-gln-arg-arg-amc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O

• Molecular Weight:

  715.80

• References & Citations:

  [1]Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35(14):1832-46.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported