Macropa-NH2 (hydrochloride)

Macropa-NH2 (hydrochloride)

• CAS Number: 2443966-86-5
• UNSPSC Description: Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/macropa-nh2-hydrochloride.html
• Purity: 99.51
• Solubility: DMSO : 83.33 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
• Smiles: O=C(O)C1=NC(CN2CCOCCOCCN(CC3=NC(C(O)=O)=CC=C3)CCOCCOCC2)=CC(N)=C1.[H]Cl
• Molecular Weight: 584.06
• References & Citations: [1]Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.J Nucl Med. 2021 Aug 12;jnumed.121.262459.|Patent. US20210236667A1.|Sci Rep. 2020 Dec 17;10(1):22203.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported