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Macropa-NH2 (hydrochloride)

CAT:
804-HY-111895A-02
Size:
5 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Macropa-NH2 (hydrochloride) - image 1

Macropa-NH2 (hydrochloride)

  • CAS Number: 2443966-86-5
  • UNSPSC Description: Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].
  • Target Antigen: Others
  • Type: Reference compound
  • Related Pathways: Others
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/macropa-nh2-hydrochloride.html
  • Purity: 99.51
  • Solubility: DMSO : 83.33 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
  • Smiles: O=C(O)C1=NC(CN2CCOCCOCCN(CC3=NC(C(O)=O)=CC=C3)CCOCCOCC2)=CC(N)=C1.[H]Cl
  • Molecular Weight: 584.06
  • References & Citations: [1]Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.J Nucl Med. 2021 Aug 12;jnumed.121.262459.|Patent. US20210236667A1.|Sci Rep. 2020 Dec 17;10(1):22203.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
  • Clinical Information: No Development Reported